Advanced Adult Hematologic Malignancies and Blood and Marrow Transplant Fellowship
The Division of Hematology and Oncology at the University of California San Francisco offers specialized training for physicians interested in adult hematologic malignancies and blood and marrow transplantation (BMT). This intensive one-year fellowship is designed to prepare physicians for academic careers in hematologic malignancies and transplantation. Our transplant program is very active, with over 190 transplants performed annually and 10 departmental faculty members capable of serving as clinical preceptors and research mentors. Active clinical and translational research programs cover a board range of topics including the development of novel conditioning regimens, hematopoiesis, leukemia, lymphoma, and multiple myeloma biology, graft vs. host disease, and immunotherapy.
Goals & Objectives:
- Preparation for successful career in hematologic malignancies and blood and marrow transplantation (BMT) in an academic setting.
- In-depth exposure to multidisciplinary approaches to hematological malignancies from BMT and non-BMT perspectives.
- Conduct research in the field of hematologic malignancies and BMT.
- To improve medical knowledge, and overall subspecialty competence related to the areas of Hematology and Oncology.
There is no board certification in BMT. ACGME Guidelines do not apply to this fellowship-training program. Graduates of this fellowship will receive recognition of the additional hematologic malignancy and BMT training from UCSF, a FACT-accredited institution. FACT is the Foundation for the Accreditation of Cellular Therapies.
Clinical & Research Components
The Hematologic Malignancy/BMT fellowship is a one year program and the fellow will participate in all activities of the Hematologic Malignancy/BMT group. An outline of the typical rotation schedule follows; it can be tailored slightly to fit specific career interests.
Inpatient BMT – 4 Months
- Time spent in clinical Hematologic Malignancy/BMT service will focus on the fellow acquiring experience in the diagnosis and treatment of hematologic malignancies, preparative therapy for transplantation, blood and marrow harvesting, peripheral stem cell and blood marrow infusions, management of acute and chronic GVHD and supportive care of the transplanted patient. The fellow is expected to take night phone calls on a rotational basis with another fellow during this inpatient time.
Outpatient BMT – 6 Months
- Time spent in the outpatient clinic will focus on BMT patients pre and post transplant as well as the management of graft-versus host disease and the general approach to the outpatient management of various hematologic malignancies. This will include attendance at the bi-weekly unrelated-donor and umbilical cord selection meeting. During the outpatient rotation, experience will be gained on the Transplant Infectious Disease service, Radiation Oncology clinic, the BMT clinical laboratory, and the Tissue Typing laboratory.
Research – 2 Months
- Fellows are expected to conduct clinical or laboratory-based research during the year of the fellowship training in an area of interest in hematologic malignancy and/or BMT.
- Fellows are expected to attend the annual American Society of Blood and Marrow Transplant Tandem meeting and/or the annual American Society of Hematology meetings. Other meetings, such as ASCO, will be on an ad hoc basis. Supervision and patient care responsibilities The non-ACGME Hematologic Malignancy/BMT fellow will be supervised by an attending when seeing patients. The fellow will be responsible for follow-up on transplant patient related issues, such as changes in immunosuppression. Fellows will participate in informed consent conferences and in weekly Transplant Rounds for discussion of new and pending BMT candidates. Fellows will interact with the hematology malignancy/BMT clinic practice nurses regarding phone calls and urgent problems related to transplant patients.
- Lumbar puncture
- Central Line Removal
- Bone Marrow aspiration and biopsy (diagnostic)
- Apheresis procedures
- Blood transfusion
- HLA tissue-typing interpretation
- Bone marrow harvest
- Hematopoietic cell cryopreservation
- Skin biopsy
- Hematopoietic cell infusion
All fellows attend a weekly Hematology/Oncology Clinical Case Conference and a weekly Hematology/Oncology Journal Club, as well as monthly Morbidity and Mortality conference, and a monthly Research in Progress lecture. Fellows present an average of one conference per year (i.e. two lectures per year). Fellows are also expected to attend the monthly hematopathology conference and the monthly unrelated-donor selection meeting. Additional research seminars are readily available throughout the Helen Diller Family Comprehensive Cancer Center. Fellows are expected to present one talk on their research and related hematologic malignancy/BMT topic at the ‘research in progress’ lecture series and/or present their research at the annual Hematology/Oncology divisional research retreat.
Specific training and documented competency in each of the following areas:
- General Knowledge
- Indications for blood and marrow transplantation
- Documentation and reporting of patients on investigational protocols
- Understanding the role of the Institutional Review Board and the ethical conduct in clinical trials
- Pre-transplantation patient education
- Identification and selection of stem cell source including use of donor registries
- Methodology and implications of HLA typing
- Understanding of chimerism analysis
- Knowledge of leukapheresis procedure
- Knowledge of blood and marrow processing and cryopreservation procedures
- Management of ABO incompatible hematopoietic progenitor cell products
- Administration of high-dose chemotherapy
- Chemotherapy and radiation therapy-induced toxicities
- Veno-occlusive disease of the liver
- Interstitial pneumonia
- CMV infection and disease
- Other viral infections in immunocompromised hosts
- Fungal disease
- Hemorrhagic cystitis
- Acute and chronic graft-versus-host disease
- Late complications of blood and marrow transplantation’
- Neutropenic fever
- Thrombocytopenia and bleeding
- Nausea and vomiting
- Terminal care patients
Eligibility and Application
Candidates must be board certified in Internal Medicine and be board eligible or board certified graduates of an accredited US Hematology and/or Medical Oncology fellowship program. Due to funding restrictions, applicants must be U.S. Citizens, U.S. Permanent Residents or have a J1 Via (H1B Visas are not accepted). Applicants must be eligible for a California Medical License.
- One fellow per year.
How to Apply
Download application and submit completed application in PDF form to Mari Collings (firstname.lastname@example.org). We require the following supporting documents to be submitted before your application will be considered:
Required Documents for Advanced Adult Hematologic Malignancies and Blood and Bone Marrow Transplant Fellowship
- Applicants must be U.S. Citizens, U.S. Permanent Residents or have a J1 Via (H1B Visas are not accepted)
- Completed Application (application)
- Curriculum Vitae
- Personal Statement, specifically addressing your academic goals and research interests as well as intent to single board in Hematology or Oncology or double board in Hematology and Oncology
- Two letters of recommendation: One letter should be from your current Program Director, Department Chair or Residency Training Program Director. At least one letter should address your clinical abilities and medical knowledge.
- For applicants with prior research experience, one letter should be from your research advisor. (The research advisor should mention the background and interest in academic Hematology and Medical Oncology as a career and a view of your competence to engage in scientific research)
- Examination Requirements:
- US Medical School Graduates – USMLE Parts I, II, and III or FLEX and be board certified in Internal Medicine.
- International Medical Graduates – UCFMG Certificate, FMGEMS, and, if not a Citizen or Permanent Resident, a copy of a current Visa, documentation of successful completion of the language skills exam and be board certified in Internal Medicine.
- Photos are appreciated
- Women and Minority Recruitment: The Fellowship Program actively recruits both women and minority candidates.
Inquiries regarding the Program can be directed to:
UCSF – Hematology/Oncology