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2012 Faculty Research Lecture in Clinical Science –
Dr. Eric J. Small

The UCSF Academic Senate has selected Eric J. Small, M.D., as recipient of the Eleventh Annual Faculty Research Lectureship – Clinical Science for the impact and legacy of his top-caliber work as a clinical research investigator and teacher. The Lecture, entitled “Immunotherapy for Prostate Cancer: Fact or Fiction?” took place on Monday, October 24, 2011 at 3:30pm in Cole Hall.

Among the top echelon of medical oncologists specializing in prostate cancer clinical research, Dr. Small is widely regarded as one of the world’s authorities on immunotherapeutics and novel therapies in patients with advanced prostate cancer.

Dr. Small has served as principal investigator and co-investigator on a large volume of innovative trails in prostate cancer and has been involved in the development of two agents, including a novel prostate cancer immunotherapeutic, from first-in-human studies to FDA approval.

Dr. Small has further defined the role of secondary hormonal therapy in those with androgen-sensitive prostate cancer. He led a phase III study that identified the role of ketoconazole in hormone refractory prostate cancer and defined prospectively the antiandrogen withdrawal phenomenon. These studies also helped to clarify the role of PSA as an outcomes measurement and surrogate for clinical benefit in prostate cancer trails. Dr. Small and his colleague Charles Ryan, M.D. have led the development of abiraterone, a new hormonally active agent recently approved by the FDA.

Dr. Small has mentored a new generation of researchers who will lead the field in years to come. He currently chairs the genitourinary committee of a major National Cancer Institute sponsored cooperative oncology group, and is an Associate Editor of the leading professional journal in Oncology, the Journal of Clinical Oncology.

Dr. Small received his MD from Case Western Reserve University School of Medicine. He has been on the faculty at UCSF since 1988, and Chair of the Division of Hematology and Oncology since 2009. He has also served concurrently, since 2009, as Deputy Director of the Helen Diller Family Comprehensive Cancer Center at UC San Francisco, where he is responsible for Clinical Sciences.

The Eleventh Annual Faculty Research Lecture – Clinical Science was held in Cole Hall on Monday, October 24, 2011, at 3:30pm, and was broadcast to other UCSF sites. It is available for viewing through Podcasts@UCSF.

Since 2001, this award has been bestowed on an individual member of the UCSF faculty with outstanding achievements in clinical research. Nominations are made by UCSF faculty, who consider the clinical research contributions of their colleagues and submit nominations for this prestigious award to the Academic Senate Committee on Research. Each year, the Committee on Research selects the recipient of this award.